Sleep Measurement Using Wrist-Worn Accelerometer Data Compared with Polysomnography

Abstract

This study determined if using alternative sleep onset (SO) definitions impacted accelerometer-derived sleep estimates compared with polysomnography (PSG). Nineteen participants (48%F) completed a 48 h visit in a home simulation laboratory. Sleep characteristics were calculated from the second night by PSG and a wrist-worn ActiGraph GT3X+ (AG). Criterion sleep measures included PSG-derived Total Sleep Time (TST), Sleep Onset Latency (SOL), Wake After Sleep Onset (WASO), Sleep Efficiency (SE), and Efficiency Once Asleep (SE_ASLEEP). Analogous variables were derived from temporally aligned AG data using the Cole-Kripke algorithm. For PSG, SO was defined as the first score of 'sleep'. For AG, SO was defined three ways: 1-, 5-, and 10-consecutive minutes of 'sleep'. Agreement statistics and linear mixed effects regression models were used to analyze 'Device' and 'Sleep Onset Rule' main effects and interactions. Sleep-wake agreement and sensitivity for all AG methods were high (89.0-89.5% and 97.2%, respectively); specificity was low (23.6-25.1%). There were no significant interactions or main effects of 'Sleep Onset Rule' for any variable. The AG underestimated SOL (19.7 min) and WASO (6.5 min), and overestimated TST (26.2 min), SE (6.5%), and SE_ASLEEP (1.9%). Future research should focus on developing sleep-wake detection algorithms and incorporating biometric signals (e.g., heart rate).