Palladium‐Catalyzed Domino Cyclization/Direct Aminosulfonylation Between Aryl Iodides and Amines via the Insertion of Sulfur Dioxide

Abstract

Abstract A palladium‐catalyzed domino cyclization/direct aminosulfonylation of aryl iodides with amines via the insertion of SO 2 (from SOgen) was presented. This method could produce a series of oxindole‐based sulfonamides in moderate‐to‐good yields. A scale‐up reaction and two synthetic applications demonstrated the robustness and practicality of this transformation. magnified image