Head-to-Head Comparison of [68 Ga]Ga-FAPI-46-PET/CT and [18F]F-FDG-PET/CT for Radiotherapy Planning in Head and Neck Cancer

Abstract

We demonstrate that [⁶⁸ Ga]Ga-FAPI-46 -PET/CT is useful for detecting tumor lesions in patients with HNCs. There is now a need for prospective randomized studies to confirm the role of [⁶⁸ Ga]Ga-FAPI-46 PET/CT in relation to [¹⁸F]F-FDG PET/CT in HNCs and to evaluate its impact on clinical outcome.