Microbiology Spectrum · 2022 · 25 citations · 21 references
Life SciencesInfectious DiseasesMicrobiologyEmerging Infectious DiseasesGenomicsMedical MicrobiologyDna SequencingGenome SequencingNext-generation SequencingVariant AnalysisVariant DetectionViral GenomicsClinical Next-generation SequencingNext-generation Sequencing AssaysNext-generation Sequencing IdentificationSars-cov-2 InfectionVariant Of Concern DetectionViral Genome SequencingViral Variant DetectionWhole-genome Sequencing Analysis
The manuscript described SARS-Cov-2 genotyping by VOC-NGS, which presents an ideal balance of accuracy, rapidity, and cost for detecting and globally tracking VOCs and some VOI of SARS-CoV-2. A large number of clinical samples can be tested together. Rapid introduction of new mutations at a specific site of the spike protein necessitates efficient strain detection and identification to enable choice of treatment and the application of vaccination, as well as planning public health policy.
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The Measurement of Observer Agreement for Categorical Data
J. Richard Landis, Gary G. Koch · Biometrics · 1977 · 78.9K citations · Full text
Multiple sequence alignment with hierarchical clustering
F. Corpet · Nucleic Acids Research · 1988 · 5.4K citations · Full text
Bette Korber, Will Fischer, S. Gnanakaran et al. · Cell · 2020 · 4.5K citations · Full text