Blood Cancer Journal · 2022 · 23 citations · 11 references
PharmacyHealth InformaticsOncologyCancer Drug Toxicity ManagementClinical InformaticsElectronic Health RecordsCancer RegistriesChemotherapy Toxicity ManagementHematologic Toxicity ManagementToxicity ClassificationToxicity ManagementToxicity Risk AssessmentBcr-abl InhibitorsChronic Myeloid Leukemia TherapyData Access For ResearchersElectronic Medical RecordsElectronic Records SystemsGlobal Research CollaborationLeukemia EpidemiologyLong-term Toxicity Surveillance
The natural history of chronic myeloid leukemia (CML) experienced a major change in the early 2000s with the development of the first BCR-ABL1 specific tyrosine kinase inhibitors (TKIs) [ 1 , 2 ]; however, there is limited supporting evidence from electronic health records (i.e., real-world data [RWD]). TriNetX is a global health research platform that provides researchers access to electronic medical records from healthcare organizations (HCOs) for conducting research studies. Our goal was to better define the current survival landscape of CML and the long-term toxicities so that we can have a better and updated understanding of the disease and the actual clinical practice in local, regional, and global settings.
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