Concepedia

2-Guanidyl pyridine PNA nucleobase for triple-helical Hoogsteen recognition of cytosine in double-stranded RNA

C.A. Ryan, Vladislavs Baskevics, Mārtiņš Katkevičs, Eriks Rozners

Chemical Communications · 2022 · 14 citations · 19 references

DOI

Concepts

Abstract

and molecular dynamics simulations provided insights into H-bonding interactions that stabilized V·C-G triplets. Our results provided insights for future design of improved nucleobases, which is an important step towards the ultimate goal of recognition of any sequence of dsRNA.

References

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