Effects of Short-Term Potassium Chloride Supplementation in Patients with CKD

Abstract

In patients with CKD stage G3b-4, increasing dietary potassium intake to recommended levels with potassium chloride supplementation raises plasma potassium by 0.4 mmol/L. This may result in hyperkalemia in older patients or those with higher baseline plasma potassium. Longer-term studies should address whether cardiorenal protection outweighs the risk of hyperkalemia.<b>Clinical trial number:</b> NCT03253172.