Shape-based separation of drug-treated <i>Escherichia coli</i> using viscoelastic microfluidics

Tianlong Zhang, Hangrui Liu, Kazunori Okano, Tao Tang, Kazuki Inoue, Yoichi Yamazaki, Hironari Kamikubo, Amy K. Cain, Yo Tanaka, David W. Inglis,

Lab on a Chip · 2022 · 31 citations · 39 references

Concepts

Abstract

with a higher AR (AR > 1.5) are driven to the side outlets. Further, we demonstrate that the separation performance of the viscoelastic microfluidic device is influenced by two main factors: sheath-to-sample flow rate ratio and the concentration of poly-ethylene-oxide (PEO). To the best of our knowledge, this is the first report on shape-based separation of a single species of cells smaller than 4 μm by microfluidics.

References

39