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The circSPON2/miR-331-3p axis regulates PRMT5, an epigenetic regulator of CAMK2N1 transcription and prostate cancer progression

DOIFull Paper Access

47

Citations

43

References

2022

Year

Bing Yao, Sha Zhu, Xiyi Wei, Mingkun Chen, Yangkun Feng, Zhimin Li, Xinyu Xu, Yuwei Zhang, Yang Wang, Jingwan Zhou,
Molecular Cancer

Abstract

Our findings showed that the epigenetic regulator PRMT5 aggravates PCa progression by inhibiting the transcription of CAMK2N1 and is modulated by the circSPON2/miR-331-3p axis, which may serve as a potential therapeutic target for patients with aggressive PCa.

References

YearCitations

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