Finerenone Reduces Renal RORγt γδ T Cells and Protects against Cardiorenal Damage

Abstract

The present study shows cardiac and renal protective effects of FIN in a DOCA-salt model. The cardiorenal protection was accompanied by a reduction of renal RORγt γδ T cells. The observed actions of FIN may provide a potential mechanism of its efficacy recently observed in clinical trials.