Depletion of Toxoplasma adenine nucleotide translocator leads to defects in mitochondrial morphology

Abstract

Altogether, we identified and characterized the ANT protein of T. gondii. Depletion of TgANT inhibited parasite growth and impaired apicoplast and mitochondrial biogenesis, as well as abnormal parasite division, suggesting TgANT is important for parasite growth.