Ipriflavone suppresses <scp>NLRP3</scp> inflammasome activation in host response to biomaterials and promotes early bone healing

Abstract

These results revealed an anti-inflammatory role of ipriflavone in NLRP3 inflammasome activation through improving mitochondrial function. This study provides a new strategy for the development of immune-regulated biomaterials and treatment options for NLRP3-related diseases.