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How the Chalcogen Atom Size Dictates the Hydrogen‐Bond Donor Capability of Carboxamides, Thioamides, and Selenoamides

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2022

Year

Abstract

Invited for the cover of this issue are Celine Nieuwland and Célia Fonseca Guerra of the Vrije Universiteit Amsterdam. The image depicts how the increasing atom size of the chalcogen from O to S to Se elongates the carbon-chalcogen bond in amides due to the increase in the steric Pauli repulsion and thereby enhances the amide hydrogen-bond donor strength. Read the full text of the article at 10.1002/chem.202200755.