Ceramide Kinase Inhibition Drives Ferroptosis and Sensitivity to Cisplatin in Mutant <i>KRAS</i> Lung Cancer by Dysregulating VDAC-Mediated Mitochondria Function

Abstract

Our findings depict how CERK inhibition may serve as a new key point in combination therapeutic strategy for NSCLC, specifically precision therapeutics targeting NSCLC possessing a KRAS mutation.