Parts-Per-Million of Soluble Pd⁰ Catalyze the Semi-Hydrogenation Reaction of Alkynes to Alkenes

Abstract

The synthesis of <i>cis</i>-alkenes is industrially carried out by selective semi-hydrogenation of alkynes with complex Pd catalysts, which include the Lindlar catalyst (PdPb on CaCO₃) and c-Pd/TiS (colloidal ligand-protected Pd nanoparticles), among others. Here, we show that Pd⁰ atoms are generated from primary Pd salts (PdCl₂, PdSO₄, Pd(OH)₂, PdO) with H₂ in alcohol solutions, independently of the alkyne, to catalyze the semi-hydrogenation reaction with extraordinarily high efficiency (up to 735 s^-1), yield (up to 99%), and selectivity (up to 99%). The easy-to-prepare Pd⁰ species hold other potential catalytic applications.