2Inc/Chlorotrimethns Ilane: A Mild Reducing System for the Conversion of Epoxides into Alcohols

Abstract

Abstract Reduction of epoxide into the corresponding saturated alcohol is an important synthetic transfornation. Various reagents t o bring about such a conversion have been reported in the literature1. An important aspect of such a transformation is the regioselective opening in case of unsymmetrical epoxides. Numerous modifications of the existing reducing agents have also been reported1 to meet with the regioselective requirements. Every reagent reported so far, to our knowledge, makes use of its hydride donating ability to effect the reduction.