Highly Regio‐ and Stereoselective Synthesis of Multialkylated Olefins through Carbozirconation of Alkynylboronates and Sequential Negishi and Suzuki–Miyaura Coupling Reactions

Abstract

Zwei Nobelkupplungen: Drei und vierfach alkylierte Olefine wurden auf folgendem Weg erhalten (siehe Schema): Einer Zirconocen-vermittelten Carbometallierung von 1-Alkinylboronaten folgten mehrere C-C-Bindungsbildungen mithilfe von Negishi- und Suzuki-Miyaura-Kreuzkupplungen, bei denen Alkylzinkreagentien mit β-H-Atomen und Alkylelektrophile als Kupplungspartner dienten. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.