Publication | Closed Access
Synthesis of Potential Cytotoxic α-Methylene γ-Lactams
84
Citations
5
References
1985
Year
Medicinal ChemistryBioorganic ChemistryBiochemistryNatural SciencesMedicineToxicologyAnti-cancer AgentAbstract α-Methylene γ-LactonesCancer TreatmentPharmacologyPhysiological ActivityPharmaceutical ChemistrySynthetic ChemistryToxicological MechanismNatural Product Synthesis
Abstract α-Methylene γ-lactones are known to have physiological activity, especially as cytotoxic agents, and are widely found in nature (1). However they are often toxic which makes them inappropriate for cancer treatment.
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