A RADIOIMMUNOASSAY FOR PARATHYROID HORMONE IN MAN

R. M. Lequin, W. H. L. Hackeng, W. Schopman

European Journal of Endocrinology · 1970 · 38 citations · 0 references

Concepts

Abstract

ABSTRACT With a guinea-pig antiserum against bovine PTH, human PTH could be measured in plasma. PTH-levels were expressed in terms of equivalents b/PTH per ml. In normal, adult subjects the mean plasma PTH concentration was 140 pg b-PTH eq./ml with a range of non-detectable (< 70) to 200 pg b-PTH eq./ml. Patients with primary hyperparathyroidism showed overlap with the normal range; in secondary hyperparathyroidism the levels were usually far higher. The PTH levels in patients with a variety of disorders involving calcium metabolism were studied.