SERUM SICKNESS AND ANAPHYLAXIS

Abstract

(Concluded from p. 143) <h3>MISCELLANEOUS COMPLICATIONS</h3> About 2 per cent of the patients had chills, which were never severe and were followed by a rise in temperature of 2 to 4 degrees (F.) above normal. Usually the chills appeared just prior to the rash or soon after. Fischer¹⁷⁹observed a child born dead to a normal mother ill with serum sickness. Necropsy showed petechial hemorrhages. In a similar case of his, the child survived sixteen hours and autopsy revealed profuse hemorrhages in the brain, the kidneys and the adrenal capsules. Brown¹⁸⁰reported the only blood dyscrasia; it developed immediately after an attack of accelerated serum sickness in a previously healthy 14 year old boy who received a prophylactic inoculation of tetanus serum. He had received a similar injection of tetanus serum two years before. He died in four weeks, with generalized adenopathy, splenomegaly and a white blood cell