Emerging infectious diseases · 2009 · 335 citations · 23 references
MedicineInfectious Disease ControlPreventive MedicineCommunicable Disease ControlDisease PreventionInfection PreventionDisease ControlDisease Prevention StrategiesInfectious Disease PreventionPrevention StrategiesRespiratory Disease PreventionRespiratory Infection ControlAdherenceAdherence BarriersEfficacy Against InfectionInfluenza Infection ControlPandemic RiskRespiratory Disease ManagementRespiratory Virus Transmission PreventionSurgical Masks
Many countries are stockpiling face masks for use as a nonpharmaceutical intervention to control virus transmission during an infl uenza pandemic. We conducted a prospective cluster-randomized trial comparing surgical masks, non-fi ttested P2 masks, and no masks in prevention of infl uenzalike illness (ILI) in households. Mask use adherence was self-reported. During the 2006 and 2007 winter seasons, 286 exposed adults from 143 households who had been exposed to a child with clinical respiratory illness were recruited. We found that adherence to mask use signifi cantly reduced the risk for ILI-associated infection, but <50% of participants wore masks most of the time. We concluded that household use of face masks is associated with low adherence and is ineffective for controlling seasonal respiratory disease. However, during a severe pandemic when use of face masks might be greater, pandemic transmission in households could be reduced.
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CONSORT statement: extension to cluster randomised trials
Marion Campbell, Diana R Elbourne, Douglas G. Altman · BMJ · 2004 · 2.6K citations · Full text
WH Seto, Dominic N.C. Tsang, Rwh Yung et al. · The Lancet · 2003 · 882 citations · Full text
Public Health, Infectious Disease Control, Infectious Diseases +13
Effect of handwashing on child health: a randomised controlled trial
Stephen P. Luby, Mubina Agboatwalla, Daniel R. Feikin et al. · The Lancet · 2005 · 752 citations