Angewandte Chemie · 2014 · 142 citations · 62 references
Natural SciencesChemistryCatalysisInorganic ChemistryOrganic ChemistryCross-coupling ReactionsHeterocycle SynthesisMetal CatalysisOrganic SynthesisAlkyne Cobalt ComplexesC - C Coupling ReactionsCobalt CatalysisCobalt Oxide CatalystsOxidant ChemistryOxidative CouplingTransition Metal-catalyzed Synthesis
Abstract A method for cobalt‐catalyzed, aminoquinoline‐ and picolinamide‐directed C(sp 2 )H bond alkenylation by alkynes was developed. The method shows excellent functional‐group tolerance and both internal and terminal alkynes are competent substrates for the coupling. The reaction employs a Co(OAc) 2 ⋅4 H 2 O catalyst, Mn(OAc) 2 co‐catalyst, and oxygen (from air) as a terminal oxidant.
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Efficient Activation of Aromatic C-H Bonds for Addition to C-C Multiple Bonds
Chengguo Jia, Dongguo Piao, Juzo Oyamada et al. · Science · 2000 · 819 citations