Concepedia

Carboxamide appended quinoline moieties as potential anti-proliferative agents, apoptotic inducers and Pim-1 kinase inhibitors

Yousry A. Ammar, Gamil A. M. Elhagali, Moustafa S. Abusaif, Mohamed R. Selim, Tamer Naser, Ahmed B. M. Mehany, Eman A. Fayed

Medicinal Chemistry Research · 2021 · 38 citations · 35 references

DOI

Concepts

References

35

SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules

Antoine Daina, Olivier Michielin, Vincent Zoete · Scientific Reports · 2017 · 17.1K citations · Full text

, , +16

Molecular Properties That Influence the Oral Bioavailability of Drug Candidates

Daniel F. Veber, Stephen R. Johnson, Hung‐Yuan Cheng et al. · Journal of Medicinal Chemistry · 2002 · 8.1K citations

, , +15

Simple Selection Criteria for Drug-like Chemical Matter

Ingo Muegge, Sarah L. Heald, David R. Brittelli · Journal of Medicinal Chemistry · 2001 · 1.3K citations

, , +11

Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragmental Methods:  An Analysis of ALOGP and CLOGP Methods

Arup K. Ghose, Vellarkad N. Viswanadhan, John J. Wendoloski · The Journal of Physical Chemistry A · 1998 · 794 citations

, , +17

An elevated bax/bcl-2 ratio corresponds with the onset of prostate epithelial cell apoptosis

Harris Perlman, Xuejun Zhang, Min Wei Chen et al. · Cell Death and Differentiation · 1999 · 243 citations · Full text

, , +13