Multivalent Nanoparticle Networks as Ultrasensitive Enzyme Sensors

Abstract

Nur 23 Enzymmoleküle genügen einem Bioassay, der auf dem Wechselspiel zwischen multivalenten und monovalenten supramolekularen Wechselwirkungen beruht: Ein Diferrocenyl-Ligand (rot) bewirkt die Bildung von Gold-Nanopartikelclustern, nach der Oxidation des Liganden wird bevorzugt ein konkurrierendes monovalentes Gastmolekül (blau) gebunden und das Aggregat zerfällt. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.