AZIRINOMYCIN. II

Abstract

Azirinomycin is a new antibiotic and is the first example of a natural product containing an azirine ring. It was isolated by ion-exchange and solvent extraction and is unstable, especially in concentrated form. It was identified as 3-methyl-2(2H) azirinecarboxylic acid by spectral measurements of its methyl ester and by identification of L-a-aminobutyric acid as a hydrogenation product.