Xenobiotica · 1977 · 49 citations · 16 references
Life SciencesAnimal SciencesBiochemistryEquine ScienceHormone BiochemistrySteroid BiochemistryGonadal Steroid HormonesSteroid CatabolismSteroid Hormone BiochemistrySteroid MetabolismSteroid StructureAnabolic Androgenic SteroidsAnabolic HormonesColumn ChromatographySteroid Hormone MetabolismSteroid Metabolite AnalysisSteroid Metabolite ProfilingUrinary Steroid Analysis
1. The metabolism of 19-nortestosterone in a cross-bred horse has been studied using 14C-labelled material.2. Two neutral metabolites isolated from urinary extracts by column chromatography were identified as isomers of 3-hydroxyestran-17-one and estrane-3,17-diol by g.l.c.-mass spectrometry.3. The stereochemistry of the two metabolites has been investigated by comparison of the retention times of their trimethylsilyl derivatives with those of standard steroids of known configuration.
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