Synthesis of Aryl(di)azinyl Ketones through Copper‐ and Iron‐catalyzed Oxidation of the Methylene Group of Aryl(di)azinylmethanes

Abstract

Nachhaltige Oxidationen von Aryl(di)azinylmethanen zu Aryl(di)azinylketonen gelingen mit Kupfer- und Eisenkatalysatoren sowie O2 als Oxidationsmittel. Die Nützlichkeit der Methode wird durch die Synthese von 6-(4-Methylbenzoyl)pyridin-2-carbaldehyd, einer Zwischenstufe bei der Herstellung des Wirkstoffs Acrivastin, illustriert. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.