Concepedia

Cytochrome P450-inducing antiepileptics increase the clearance of vincristine in patients with brain tumors

K VILLIKKA, K KIVISTO, H MAENPAA, H JOENSUU, P NEUVONEN

Clinical Pharmacology & Therapeutics · 1999 · 19 citations · 0 references

Concepts

MedicinePharmacokineticsPharmacologyChemotherapyEpilepsyNeuro-oncologyAntiepileptic PharmacologyAntiepileptic PharmacotherapyBlood-brain Barrier PenetrationBrain TumorsCentral Nervous System Tumor PharmacotherapyCytochrome P450 InteractionsAntiepileptic Drug InteractionsAntiepileptic-chemotherapy InteractionsCyp450-mediated InteractionsCytochrome P450 Enzyme Inhibition