The Versatility of <i>Helicobacter pylori</i> CagA Effector Protein Functions: the Master Key Hypothesis

Abstract

In the article by Backert et al. published in HELICOBACTER volume 15, pages 163–176, we noted on page 173 a possible conflict between three studies on the role of the putative chaperone CagF for injection/phosphorylation of the effector protein CagA in Helicobacter pylori. However, we have overseen a published Erratum for one of these studies (Molecular Microbiology 2003, vol. 47: 1759) which corrected the reported the error. Thus, there is no conflict because deletion of cagF gene in H. pylori is indeed is necessary for CagA phosphorylation.