Science · 1970 · 212 citations · 4 references
MedicinePharmaceuticsPharmacologyImmunotechnologyImmunoassay AnalysisImmunoassay DevelopmentOpioid AnalgesicsOpioid PharmacologyRadiopharmaceuticalsAssayAssay Specificity
The development of a radioimmunoassay for morphine is described. The hapten morphine is made antigenic by coupling it to a protein at the phenolic group of the molecule. Extremely low concentrations of morphine (0.5 nanogram) can be measured by this assay procedure.
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