Novel imidazole derivatives with subtype-selective antimuscarinic activity

Pirenzepine distinguishes between different subclasses of muscarinic receptors

Rudolf Hammer, Christopher P. Berrie, N.J.M. Birdsall et al. · Nature · 1980 · 1.3K citations

Medicine, Neuroscience, Pharmacology +16

A COMPARISON OF AFFINITY CONSTANTS FOR MUSCARINE‐SENSITIVE ACETYLCHOLINE RECEPTORS IN GUINEA‐PIG ATRIAL PACEMAKER CELLS AT 29°C AND IN ILEUM AT 29°C AND 37°C

R. B. BARLOW, K.J. BERRY, Patricia A. Glenton et al. · British Journal of Pharmacology · 1976 · 292 citations · Full text

Medicine, Biochemistry, Pharmacology +16

Differential blockade of muscarinic receptor subtypes by polymethylene tetraamines. Novel class of selective antagonists of cardiac M-2 muscarinic receptors

Carlo Melchiorre, Anna Cassinelli, Wilma Quaglia · Journal of Medicinal Chemistry · 1987 · 137 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Analogs of oxybutynin. Synthesis and antimuscarinic and bladder activity of some substituted 7-amino-1-hydroxy-5-heptyn-2-ones and related compounds

J. Paul Carter, Lalita Noronha‐Blob, Vicki H. Audia et al. · Journal of Medicinal Chemistry · 1991 · 28 citations

Medicine, Medicinal Chemistry, Pharmacology +6