Tumor necrosis factor.

An endotoxin-induced serum factor that causes necrosis of tumors.

E A Carswell, Lloyd J. Old, Robert Kassel et al. · Proceedings of the National Academy of Sciences · 1975 · 4.5K citations · Full text

Veterinary Medicine, Immunology, Pathobiology +15

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

Gray D. Shaw, Robert Kamen · Cell · 1986 · 4.1K citations

Life Sciences, Genetics, Molecular Biology +14

Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia

Kevin J. Tracey, Yuman Fong, David Hesse et al. · Nature · 1987 · 2.5K citations

Veterinary Medicine, Immunology, Infectious Diseases +16

Endothelial Leukocyte Adhesion Molecule 1: an Inducible Receptor for Neutrophils Related to Complement Regulatory Proteins and Lectins

M P Bevilacqua, Siegfried Stengelin, Michael A. Gimbrone et al. · Science · 1989 · 2K citations

Life Sciences, Immunology, Molecular Biology +17

Tumor Necrosis Factor (TNF)

Lloyd J. Old · Science · 1985 · 1.9K citations

Life Sciences, Immunology, Oncology +12