A Homo [3+2] Dipolar Cycloaddition: The Reaction of Nitrones with Cyclopropanes

Abstract

Für Naturstoffsynthese geeignet: Cyclopropandicarbonsäurediester reagieren mit Nitronen in Gegenwart von Ytterbiumtriflat in einer [3+2]-Cycloaddition diastereoselektiv zu Tetrahydro-1,2-oxazinen (siehe Schema). Mit dieser Methode lässt sich das Grundgerüst von FR-900482 in zwei Stufen aufbauen. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2001/2003/z51573_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.