Monoclonal Antibody Production Using a New Supermacroporous Cryogel Bioreactor

Continuous cultures of fused cells secreting antibody of predefined specificity

Georges Köhler, César Milstein · Nature · 1975 · 17.2K citations

Pharmacy, Cell Biology, Immunology +11

Characterization of the antibody response in mice with type II collagen–induced arthritis, using monoclonal anti–type II collagen antibodies

Rikard Holmdahl, Kristofer Rubin, Lars Klareskog et al. · Arthritis & Rheumatism · 1986 · 396 citations

Medicine, Immunology, Pathobiology +14

Collagen Type II-Specific Monoclonal Antibody-Induced Arthritis in Mice

Kutty Selva Nandakumar, L Svensson, Rikard Holmdahl · American Journal Of Pathology · 2003 · 303 citations · Full text

Medicine, Immunology, Pathobiology +10

Disposable bioreactor for cell culture using wave-induced agitation

Vijay Singh · Cytotechnology · 1999 · 300 citations · Full text

Engineering, Bioengineering, Biotechnology +15

Chromatography of microbial cells using continuous supermacroporous affinity and ion-exchange columns

Pär Arvidsson, Fatima M. Plieva, Irina N. Savina et al. · Journal of Chromatography A · 2002 · 243 citations

Pharmacy, Microbiology, Microbial Biotechnology +8