Botanical Sciences · 1997 · 129 citations · 15 references
Genetic TestingMolecular MarkersGeneticsGenetic EpidemiologyCo-dominant MarkersPathologyHuman PolymorphismDna AnalysisGenomicsGenetic AnalysisMolecular EcologyMolecular Marker TechniquesBiostatisticsPublic HealthMolecular DiagnosticsStatistical GeneticsMolecular BreedingGenetic VariationMedicine
Molecular markers are becoming essential tools in many areas of biology including bio-medicine, breeding, forensics and diversity analysis. In addition they are also being exploited to locate and isolate genes of interest. A variety of DNA based molecular marker techniques are now available. Individual techniques employ different methods used routinely in molecular biology and different kinds of markers are distinguished by their capacity to detect polymorphism at one or many loci and whether they are dominant or co-dominant markers. The choice of marker system will depend on individual laboratory facilities and the applications of interest to each researcher.
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DNA polymorphisms amplified by arbitrary primers are useful as genetic markers
John G. Williams, Anne R. Kubelik, Kenneth J. Livak et al. · Nucleic Acids Research · 1990 · 13.1K citations · Full text
AFLP: a new technique for DNA fingerprinting
Pieter Vos, René C. J. Hogers, Marjo Bleeker et al. · Nucleic Acids Research · 1995 · 12.4K citations · Full text
Construction of a genetic linkage map in man using restriction fragment length polymorphisms.
David Botstein, R. White, Mark H. Skolnick et al. · PubMed · 1980 · 8.4K citations
Fingerprinting genomes using PCR with arbitrary primers
John Welsh, Michael McClelland · Nucleic Acids Research · 1990 · 5.2K citations · Full text