RANDOMISED TRIAL OF INTRAVENOUS STREPTOKINASE, ORAL ASPIRIN, BOTH, OR NEITHER AMONG 17 187 CASES OF SUSPECTED ACUTE MYOCARDIAL INFARCTION: ISIS-2

Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples

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Beta blockade during and after myocardial infarction: An overview of the randomized trials

Salim Yusuf, Richard Peto, John A. Lewis et al. · Progress in Cardiovascular Diseases · 1985 · 3.2K citations

Medicine, Cardiology, Pharmacology +15

EFFECTIVENESS OF INTRAVENOUS THROMBOLYTIC TREATMENT IN ACUTE MYOCARDIAL INFARCTION

GRUPPOITALIANOPERLOSTUDIODELL · The Lancet · 1986 · 2.5K citations

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Thrombolysis in Myocardial Infarction (TIMI) Trial, Phase I: A comparison between intravenous tissue plasminogen activator and intravenous streptokinase. Clinical findings through hospital discharge.

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Medicine, Cardiology, Pharmacotherapy +13

Secondary prevention of vascular disease by prolonged antiplatelet treatment

BMJ · 1988 · 1K citations

Medicine, Pharmacology, Pharmacotherapy +13