Diabetes complications in 1952 type 2 diabetes mellitus patients managed in a single institution

JamalS Alwakeel, Riad A. Sulimani, Hani Al‐Asaad, Ali Alharbi, Nauman Tarif, Abdulkareem Alsuwaida, Sulaiman Al-Mohaya, Arthur Isnani, Awatif Alam, Durdana Hammad

Annals of Saudi Medicine · 2008 · 25 citations · 11 references

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Abstract

<b>Background and Objectives: </b> Because there is no recent update on the state of diabetes and its concomi--tant complications in Saudi Arabia<sup> , </sup> we undertook a study of the prevalence of health complications in patients with type 2 diabetes mellitus admitted to our institution.<b> Methods:<sup></b> </sup> We conducted a retrospective review of medical records of adult Saudi patients with type 2 diabetes who were seen in clinics or admitted to the Security Forces Hospital<sup> , </sup> Riyadh<sup> , </sup> Saudi<sup> </sup> Arabia<sup> , </sup> between January 1989 and January 2004.<b> Results: </b> Of 1952 patients<sup> , </sup> 943 (48.3&#x0025;) were males. For the whole study population the mean age at enrollment was 58.4&#x00B1;14.2 years<sup> , </sup> the mean age at onset of diabetes was 48.1&#x00B1;12.8 years<sup> , </sup> the mean duration of diabetes was 10.4&#x00B1;7.5 years<sup> , </sup> and the mean duration of follow-up was 7.9&#x00B1;4.6 years. Nephropathy was the most prevalent complication<sup> , </sup> occurring<sup> </sup> in<sup> </sup> 626 patients (32.1&#x0025;). Acute coronary syndrome occurred in 451 (23 .1 &#x0025;), cataracts in 447 (22.9&#x0025;)<sup> , </sup> retinopathy<sup> </sup> in<sup> </sup> 326 (16.7&#x0025;)<sup> , </sup> and myocardial infarction in 279 (14.3&#x0025;)<sup> , </sup> Doubling<sup> </sup> of serum creatinine was seen in 250 (12.8&#x0025;) and 79 (4.0&#x0025;) went into dialysis. Hypertension was present in 1524 (78.1&#x0025;) and dyslipidemia in 764 (39.1&#x0025;). Overall mortality was 8.2&#x0025;. Multiple complications were <sup> frequent.</sup> Males<sup> </sup> had higher prevalence of complications than females (P&#60; .05). Mortality was significantly higher in males 92 (9.8&#x0025;) than females 69 (6.8&#x0025;) (P=.024). The prevalence of complications significantly increased with dura--tion of diabetes and age (P&#60; .05). <b> Conclusion: </b> Among Saudis, the prevalence of concomitant diabetic complications is high, with cardiovas--cular and renal complications the most frequent. Many patients had multiple complications. Early and frequent screenings in the patients with type 2 diabetes are desirable to identify patients at high risk for concomitant complications and to prevent disabilities.

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