Late Assessment of Thrombolytic Efficacy (LATE) study with alteplase 6-24 hours after onset of acute myocardial infarction

A Multiple Testing Procedure for Clinical Trials

Peter C. O’Brien, Thomas R. Fleming · Biometrics · 1979 · 3.3K citations

Public Health, Biostatistics, Evidence-based Practice +13

EFFECTIVENESS OF INTRAVENOUS THROMBOLYTIC TREATMENT IN ACUTE MYOCARDIAL INFARCTION

GRUPPOITALIANOPERLOSTUDIODELL · The Lancet · 1986 · 2.5K citations

Medicine, Cardiology, Internal Medicine +11

TRIAL OF TISSUE PLASMINOGEN ACTIVATOR FOR MORTALITY REDUCTION IN ACUTE MYOCARDIAL INFARCTION

Robert G. Wilcox, Carl Olsson, Allan M. Skene et al. · The Lancet · 1988 · 1.2K citations

Medicine, Cardiology, Internal Medicine +10

ISIS-3: a randomised comparison of streptokinase vs tissue plasminogen activator vs anistreplase and of aspirin plus heparin vs aspirin alone among 41 299 cases of suspected acute myocardial infarction

The Lancet · 1992 · 922 citations

Medicine, Cardiology, Internal Medicine +16

In-hospital mortality and clinical course of 20 891 patients with suspected acute myocardial infarction randomised between alteplase and streptokinase with or without heparin

The International Study Group · The Lancet · 1990 · 621 citations

Medicine, Cardiology, Internal Medicine +10