PubMed · 1994 · 12 citations · 0 references
PharmacyPharmaceutical AnalysisPharmacologyBiochemical PharmacologyDrug DiscoveryMass Spectrometric AnalysisDrug MonographsPharmaceutical Calculations
In this report, an accurate method for quantitatively analysing the 6,7-dimethylesculetin and capillarisine in Artemisia capillaris and the prescriptions containing the crude drug has been established by three dimension gradient HPLC, by which the trace amount of these compounds in the samples can be determined. 6,7-Dimethylesculetin is calculated by the regression equation Y = 84.15X-0.023 (r = 1.000), and capillarisine is calculated by Y = 62.17X - 0.149 (r = 1.000). In the formula, Y represents concentration of compounds and X represents area of the peak.