CHK1 frameshift mutations in genetically unstable colorectal and endometrial cancers

A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer.

C. Richard Boland, Stephen N. Thibodeau, Stanley R. Hamilton et al. · PubMed · 1998 · 4.1K citations

Life Sciences, Genetics, Oncology +17

A transforming growth factor beta receptor type II gene mutation common in colon and gastric but rare in endometrial cancers with microsatellite instability.

Lois L. Myeroff, Ramon Parsons, Seong‐Jin Kim et al. · PubMed · 1995 · 445 citations

Life Sciences, Genetics, Oncology +13

The ATM gene and susceptibility to breast cancer: analysis of 38 breast tumors reveals no evidence for mutation.

Igor Vořechovský, Debora Rasio, Lu Luo et al. · PubMed · 1996 · 149 citations

Life Sciences, Genetics, Molecular Genetics +16

Somatic frameshift mutations in DNA mismatch repair and proapoptosis genes in hereditary nonpolyposis colorectal cancer.

Hiroyuki Yamamoto, Hisako Sawai, Thomas K. Weber et al. · PubMed · 1998 · 140 citations

Life Sciences, Genetics, Oncology +17

The BAX gene, the promoter of apoptosis, is mutated in genetically unstable cancers of the colorectum, stomach, and endometrium.

Hong Ouyang, Toru Furukawa, Tatsuya Abé et al. · PubMed · 1998 · 108 citations

Life Sciences, Genetics, Oncology +16