Detection of Early-Stage Pancreatic Adenocarcinoma

David V. Gold, Michael Goggins, David E. Modrak, Guy Newsome, Mengling Liu, Chanjuan Shi, Ralph H. Hruban, David M. Goldenberg

Cancer Epidemiology Biomarkers & Prevention · 2010 · 45 citations · 26 references

DOIFull text

Open access

Abstract

These results suggest the use of the PAM4 serum assay to detect early-stage pancreatic adenocarcinoma and that positive levels of PAM4 antigen are not derived from inflamed pancreatic tissues but rather may provide evidence of subclinical pancreatic neoplasia. EFFECT: The ability to detect pancreatic adenocarcinoma at an early stage could provide for early therapeutic intervention with potentially improved patient outcomes.

References

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