Synthesis of Mitomycin C and decarbamoylmitomycin C N6 deoxyadenosine-adducts

Mitomycin, a new antibiotic from Streptomyces. I.

T. Hata, Takeshi Hoshi, K Kanamori et al. · PubMed · 1956 · 198 citations

Life Sciences, Microbiology, Chemotherapy +2

A New Mechanism of Action for the Anticancer Drug Mitomycin C: Mechanism-Based Inhibition of Thioredoxin Reductase

Manuel M. Paz, Xu Zhang, Jun Lu et al. · Chemical Research in Toxicology · 2012 · 120 citations

Life Sciences, Biochemistry, Pharmacology +14

Analysis of 1H chemical shifts in DNA: Assessment of the reliability of 1H chemical shift calculations for use in structure refinement

Sybren S. Wijmenga, Martijn Kruithof, Cees W. Hilbers · Journal of Biomolecular NMR · 1997 · 94 citations

Life Sciences, Biochemistry, Chemistry +9

Relative Toxicities of DNA Cross-Links and Monoadducts:  New Insights from Studies of Decarbamoyl Mitomycin C and Mitomycin C

Yolanda Palom, Gopinatha Suresh Kumar, Li-Qian Tang et al. · Chemical Research in Toxicology · 2002 · 90 citations

Pharmacy, Oncology, Toxicology +12

New strategy for the synthesis of oligodeoxynucleotides bearing adducts at exocyclic amino sites of purine nucleosides

Constance M. Harris, Liang Zhou, Eric A. Strand et al. · Journal of the American Chemical Society · 1991 · 90 citations

Pharmacy, Biochemistry, Chemistry +10