Lewis Base‐Promoted Ring‐Opening 1,3‐Dioxygenation of Unactivated Cyclopropanes Using a Hypervalent Iodine Reagent

Abstract

Abstract A facile and effective system has been developed for the regio‐ and chemoselective ring‐opening/electrophilic functionalization of cyclopropanes through C−C bond activation by [bis(trifluoroacetoxy)iodo]benzene with the aid of the Lewis basic promoter p ‐toluenesulfonamide. The p ‐toluenesulfonamide‐promoted system works well for a wide range of cyclopropanes, resulting in the formation of 1,3‐diol products in good yields and regioselectivity.