Concepedia

Structure and property based design, synthesis and biological evaluation of γ-lactam based HDAC inhibitors

Eunhyun Choi, Chulho Lee, Jung Eun Park, Jeong Jea Seo, Misun Cho, Jong Soon Kang, Hwan Mook Kim, Song‐Kyu Park, Kiho Lee, Gyoonhee Han

Bioorganic & Medicinal Chemistry Letters · 2010 · 34 citations · 7 references

DOI

Concepts

References

7

Synthesis, enzymatic inhibition, and cancer cell growth inhibition of novel δ-lactam-based histone deacetylase (HDAC) inhibitors

Hwan Mook Kim, Kiho Lee, Bum Woo Park et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 33 citations · Full text

, , +16

Structure−Activity Relationship Studies of a Series of Novel δ-Lactam-Based Histone Deacetylase Inhibitors

Hwan Mook Kim, Dong-Kyu Ryu, Yongseok Choi et al. · Journal of Medicinal Chemistry · 2007 · 28 citations · Full text

, , +16

Modification of cap group in δ-lactam-based histone deacetylase (HDAC) inhibitors

Hwan Mook Kim, Sung Hee Hong, Myung Sook Kim et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 26 citations · Full text

, , +10

A novel δ-lactam-based histone deacetylase inhibitor, KBH-A42, induces cell cycle arrest and apoptosis in colon cancer cells

Moo Rim Kang, Jong Soon Kang, Sang‐Bae Han et al. · Biochemical Pharmacology · 2009 · 23 citations

, , +16

<b><i>In vitro</i></b>metabolism of KBH-A40, a novel<b>δ</b>-lactam-based histone deacetylase (HDAC) inhibitor, in human liver microsomes and serum

H. M. Kim, Soo Jin Oh, S.-K. Park et al. · Xenobiotica · 2008 · 14 citations

, , +16