Facile Synthesis of Copper(II)Immobilized on Magnetic Mesoporous Silica Microspheres for Selective Enrichment of Peptides for Mass Spectrometry Analysis

Abstract

Fesselnde Poren: Kupferionen wurden in den senkrechten Kanälen einer mesoporösen SiO2-Schale um einen Fe3O4-Kern immobilisiert. Dank der gut zugänglichen Mesoporen, der großen Porenoberfläche und der großen Menge an Cu2+-Ionen in den Kanälen gelingt der selektive Einfang von hydrophoben und hydrophilen Peptiden aus komplexen biologischen Proben mit anschließender magnetischer Abtrennung und MS-Analyse (siehe Bild). Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.