Are MDCK Cells Transfected with the Human MRP2 Gene a Good Model of the Human Intestinal Mucosa?

MDCK (Madin-Darby Canine Kidney) Cells: A Tool for Membrane Permeability Screening

Jennifer D. Irvine, Lori H. Takahashi, Karen Lockhart et al. · Journal of Pharmaceutical Sciences · 1999 · 976 citations

Life Sciences, Biochemistry, Cell Biology +13

The multidrug resistance protein family

Piet Borst, Raymond Evers, Marcel Kool et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1999 · 650 citations

Life Sciences, Molecular Biology, Pharmacology +12

Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA.

Raymond Evers, Marcel Kool, Liesbeth van Deemter et al. · Journal of Clinical Investigation · 1998 · 615 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

In vitro and in vivo reversal of multidrug resistance by GF120918, an acridonecarboxamide derivative.

François Hyafil, Catherine Vergely, Philippe Vignaud et al. · PubMed · 1993 · 529 citations

Medicine, Medicinal Chemistry, Pharmacology +11

Correlation of Gene Expression of Ten Drug Efflux Proteins of the ATP-Binding Cassette Transporter Family in Normal Human Jejunum and in Human Intestinal Epithelial Caco-2 Cell Monolayers

Jan Taipalensuu, Hans Törnblom, Greger Lindberg et al. · Journal of Pharmacology and Experimental Therapeutics · 2001 · 444 citations

Medicine, Cell Biology, Pharmacology +13