Expression of the RESA Gene in <i>Plasmodium falciparum</i> Isolate FCR3 Is Prevented by a Subtelomeric Deletion

Abstract

We show here that the Plasmodium falciparum isolate FCR3 does not express the ring-infected erythrocyte surface antigen (RESA). This is because the 5' end of the RESA gene has been inverted and partly deleted and a telomere has been added to it. We propose a model to explain these events.