Chemistry for peptide and protein PEGylation

Alteration of immunological properties of bovine serum albumin by covalent attachment of polyethylene glycol.

Abraham Abuchowski, T. van Es, Nicholas C. Palczuk et al. · Journal of Biological Chemistry · 1977 · 1.4K citations · Full text

Life Sciences, Biochemistry, Clinical Biochemistry +7

Effect of covalent attachment of polyethylene glycol on immunogenicity and circulating life of bovine liver catalase.

Abraham Abuchowski, Judy McCoy, Nicholas C. Palczuk et al. · Journal of Biological Chemistry · 1977 · 1.3K citations · Full text

Life Sciences, Biochemistry, Immunology +14

Controlled Delivery Systems for Proteins Based on Poly(Lactic/Glycolic Acid) Microspheres

Smadar Cohen, Toshio Yoshioka, Melissa Lucarelli et al. · Pharmaceutical Research · 1991 · 845 citations

Pharmacy, Biomedical Engineering, Pharmaceutics +14

Rational Design of a Potent, Long-Lasting Form of Interferon:  A 40 kDa Branched Polyethylene Glycol-Conjugated Interferon α-2a for the Treatment of Hepatitis C

Pascal Bailon, Alicia V. Palleroni, Carol Ann Schaffer et al. · Bioconjugate Chemistry · 2001 · 611 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Chemistry of polyethylene glycol conjugates with biologically active molecules

Samuel Zalipsky · Advanced Drug Delivery Reviews · 1995 · 549 citations

Pharmacy, Chemistry, Medicinal Chemistry +13