Annual Review of Biochemistry · 1986 · 495 citations · 0 references
Life SciencesDevelopmental BiologyMolecular BiologyCell SignalingGene ExpressionSignal TransductionDevelopmental ProliferationDevelopmental Signaling PathwaysMorphogen SignalingPathway RegulationRna TranscriptionCell Fate Decision SignalingCell Growth RegulationCell Growth Signaling PathwaysHippo SignalingHippo Signaling PathwayOrgan Size ControlTissue GrowthTissue Growth Regulation
The Hippo pathway was initially discovered in Drosophila melanogaster as a key regulator of tissue growth. It is an evolutionarily conserved signaling cascade regulating numerous biological processes, including cell growth and fate decision, organ size ...Read More