Mycologia · 1999 · 11 citations · 0 references
MedicineMicrobiologyNephrologyMedical MicrobiologyRenal PathologyRenal PathophysiologyFungal MorphologyRenal Cystic DiseasesRenal DiseaseNew Species DescriptionPure Culture IsolationPure Culture MaintenanceRenal Organ CultureRenal Pathogenesis
As part of a study of polycystic kidney disease (PKD), epithelial cells were isolated and propagated from cyst walls of human kidneys obtained at nephrectomy. A Penicillium species was found growing with the epithelial cells in some culture flasks. It was monoverticillate and somewhat resembled P. restrictum but differed morphologically from this and all other Penicillium species. Two strains of this fungus were isolated in pure culture and described as the new species Penicillium pimiteouiense. Ochratoxin A production was not detected in P. pimiteouiense. The role, if any, that this fungus plays in polycystic kidney disease is not known.